Chorionic Villus Sampling (CVS): Precision in Genetic Insight at Cradle Fertility
Chorionic Villus Sampling (CVS) stands as a key diagnostic tool in the realm of prenatal care, offering a meticulous examination of fetal chromosomes for a comprehensive understanding of genetic health.
Information Obtained from CVS
The primary objective of CVS is to collect a small sample of cells from the placenta, known as chorionic villi. These cells are then analysed to provide detailed information about:
- Chromosomal Abnormalities: CVS is highly effective in detecting chromosomal abnormalities, including common trisomies such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13).
- Genetic Disorders: Genetic testing during CVS can identify specific genetic disorders based on known family history or parental carrier status.
When is CVS Recommended?
CVS is typically recommended in specific situations, including:
- Advanced Maternal Age: Women aged 35 or older have a higher likelihood of chromosomal abnormalities in their offspring. CVS is often suggested to assess fetal chromosomes in such cases.
- Abnormal Prenatal Screening Results: Abnormal results from initial prenatal screening tests, such as the first-trimester screening may prompt the recommendation for CVS to confirm or refute potential genetic concerns.
- Family History of Genetic Conditions: If there is a known family history of certain genetic conditions or chromosomal disorders, Chorionic villus sampling can provide detailed genetic information about the fetus.
- Previous Child with Genetic Disorders: Parents who have had a previous child with a chromosomal abnormality may opt for CVS in subsequent pregnancies to assess genetic risks.
- Ultrasound Findings: Abnormalities detected during an ultrasound, such as structural concerns or growth issues, may lead to the recommendation for CVS to obtain detailed genetic insights.
Differences between Amniocentesis and Chorionic Villus Sampling
Since both the tests serve the same purpose, a common question might come as to what is someone asked for amniocentesis while another for CVS. Though both are prenatal genetic diagnostic tools, there are notable differences between the two procedures, ranging from when they are performed to the types of samples collected.
- Timing of the Procedure:
- Amniocentesis: Typically performed between weeks 15 and 20 of pregnancy.
- CVS: Generally conducted between weeks 10 and 13 of pregnancy.
- Sample Collection:
- Amniocentesis: Involves the extraction of a small amount of amniotic fluid from the amniotic sac surrounding the fetus.
- CVS: Involves the collection of a small sample of chorionic villi, which are tiny projections of placental tissue.
- Type of Cells Analyzed:
- Amniocentesis: Analyses fetal cells present in the amniotic fluid, including cells shed by the baby’s skin, urinary and digestive systems.
- CVS: Analyses cells from the placenta, specifically from the chorionic villi, which are representative of the fetal genetic makeup.
- Genetic Information Obtained:
- Both procedures provide information about chromosomal abnormalities, such as Down syndrome, Edwards syndrome, and Patau syndrome.
- Both can also offer insights into specific genetic disorders based on family history or parental carrier status.
- Risk of Miscarriage:
- Amniocentesis: Generally considered to have a lower risk of miscarriage, estimated at around 1 in 300 to 1 in 500 procedures.
- CVS: Historically associated with a slightly higher risk of miscarriage compared to amniocentesis, estimated at about 1 in 100 to 1 in 200 procedures.
- Timing of Results:
- Amniocentesis: Results are typically available within two to three weeks.
- CVS: Results are often available more quickly, usually within one to two weeks.
- Procedure Technique:
- Amniocentesis: Involves inserting a thin needle through the abdominal wall into the amniotic sac under ultrasound guidance.
- CVS: Can be performed through the abdomen (transabdominal) or through the cervix (transcervical), with the choice depending on factors such as placental location and maternal anatomy.
- Suitability for Early Detection:
- Amniocentesis: May be preferred for certain conditions, especially if a detailed analysis or additional time for decision-making is required.
- CVS: Often chosen for early detection due to its earlier timing in pregnancy.
Cradle Fertility's Approach to CVS
At Cradle Fertility, our commitment to providing the best care encompasses the precise administration of CVS, ensuring expectant parents receive accurate genetic information to guide them on their journey to parenthood. At Cradle Fertility, our approach to CVS is characterized by a commitment to precision, safety, and comprehensive care:
- Experienced Healthcare Professionals
- Comprehensive genetic counselling
- Advanced state-of-the-art technology
- Personalized support and care
Cradle Fertility is dedicated to providing precision and compassion in every step of the CVS process. By leveraging advanced technology, experienced professionals, and personalized care, we empower expectant parents with accurate genetic information, allowing them to make informed decisions for the health and well-being of their growing family. CVS at Cradle Fertility is not just a procedure; it’s a journey towards ensuring the best possible start for every new life.